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Over eight months the scientists tested 20 drugs, all with negative results. Finally they tested the anticonvulsant drug ethosuzimide. Researchers found that the drug extended the life span of roundworms from 16. 7 days to 19. 6 days, a 17 percent increase。
A. But Komfeld said scientists will not know about the applicability of the drugs in humans until a similar study is done on humans. “What’s very encouraging is that these drugs were developed to treat humans, and they are well understood, because they’ve been used for a long time, ” he said。
B. Later the scientists discovered that two related anticonvulsant drugs also lengthened the lives of the worms-in the case of one drug, by almost 50 percent. “This was a big surprise to use, Komfeld said. ”“We didn’t think anticonvulsant drugs had any particular relationship to aging. That connection was completely unexpected. ”
C. Roundworms are a poor subject for experiments, because they are not like humans, even though their molecules are similar. For example, they have no bones, nor do they show emotions, making it difficult to know how exactly human subjects would react to these drugs in large quantities. However, using the worms allows experiments to be conducted quickly, because they do not live for long。
D. “Somehow the neural activity seems to regulate the aging of all of the body the skin, musculature, and reproductive tract, ” Kornfeld said. “Somehow the nervous system coordinates the progress of all these tissues, evidently, though the life stages. But we don’t know how it does that. ”
E. The discovery may also shed light on the little-understood aging process. Since the drugs act on the neuromuscular systems of both humans and worms, the findings hint at a link between neural activity and aging。
F. Unlike vertebrates, the worms are ideal subjects for the study of aging because of their short life spans, which last only a couple of weeks in a laboratory. The worm is well known in genetics, and the worm’s genome has been sequenced。
G. Use of this drug has been permitted by law since 1998 and wider use is now expected as a result of the studies. “We can clearly link this drug with human aging, but we still need to find proof, says Kornfeld optimistically. ”
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更多 “ Over eight months the scientists tested 20 drugs, all with negative results. Finally they tested the anticonvulsant drug ethosuzimide. Researchers found that the drug extended the life span of roundworms from 16. 7 days to 19. 6 days, a 17 percent increase。A. But Komfeld said scientists will not know about the applicability of the drugs in humans until a similar study is done on humans. “What’s very encouraging is that these drugs were developed to treat humans, and they are well understood, because they’ve been used for a long time, ” he said。B. Later the scientists discovered that two related anticonvulsant drugs also lengthened the lives of the worms-in the case of one drug, by almost 50 percent. “This was a big surprise to use, Komfeld said. ”“We didn’t think anticonvulsant drugs had any particular relationship to aging. That connection was completely unexpected. ”C. Roundworms are a poor subject for experiments, because they are not like humans, even though their molecules are similar. For example, they have no bones, nor do they show emotions, making it difficult to know how exactly human subjects would react to these drugs in large quantities. However, using the worms allows experiments to be conducted quickly, because they do not live for long。D. “Somehow the neural activity seems to regulate the aging of all of the body the skin, musculature, and reproductive tract, ” Kornfeld said. “Somehow the nervous system coordinates the progress of all these tissues, evidently, though the life stages. But we don’t know how it does that. ”E. The discovery may also shed light on the little-understood aging process. Since the drugs act on the neuromuscular systems of both humans and worms, the findings hint at a link between neural activity and aging。F. Unlike vertebrates, the worms are ideal subjects for the study of aging because of their short life spans, which last only a couple of weeks in a laboratory. The worm is well known in genetics, and the worm’s genome has been sequenced。G. Use of this drug has been permitted by law since 1998 and wider use is now expected as a result of the studies. “We can clearly link this drug with human aging, but we still need to find proof, says Kornfeld optimistically. ” ” 相关考题
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The law requires all cars () for safety and efficiency.
A.being tested regularlyB.to be regularly testedC.be regularly testedD.regularly tested
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________ they are observing can be tested in a practical way, scientists will use experiments.A、IfB、All thatC、WhatD、If what
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One important factor that affects the correctness of the results is that_________．A． the old men tested may not have shown such cognitive declineB． people surveyed are all oldC． people taking part in this test came from all over the worldD． women live longer than men
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Better Control of TB Seen If a Faster Cure Is FoundThe World Health Organization estimates that about one-third of all people are infected with bacteria that cause tuberculosis（结核病）.Most times , the infection remains inactive（不活跃的）.But each year about eight million people develop active cases of TB,usually in their lungs. Two million people die of it.The disease has increased with the spread of AIDS and drug-resist-ant forms of tuberculosis.Current treatments take at least six months.Patients have to take a combination of several antibiotic（抗生素）drugs daily. But many people stop as soon as they feel better. Doing that can lead to an infection（传染病）that resists treatment. Public health experts agree that a faster-act-ing cure for tuberculosis would be more effective.Now a study estimates just how effective it might be .A professor of international health at Harvard University led the study.Joshua Salomon says a shorter treatment program would likely mean not just more patients cured.It would also mean fe- wer infectious patients who can pass on their infection to others.The researchers developed a mathematical（数学的）model to examine the effects of a two-month treatment plan.They tested the model with current TB conditions in Southeast Asia.The scientists found that a two-month treatment could prevent about twenty percent of new cases.And it might prevent about twenty-five percent of TB deaths.The model shows that these reductions would take place between two thousand twelve and two thousand thirty.That is,if a faster cure is developed and in wide use by two thousand twelve.The World Health Organization developed the DOTS program in nineteen ninety.DOTS（短期直接观察治疗）is Directly Observed Treatment, Short-course. Health workers watch tubercu- losis patients take their daily pills to make sure they continue treatment.Earlier this year,an international partnership of organizations announced a plan to expand the DOTS program.The ten-year plan also aims to finance research into new TB drugs.The four most common drugs used now are more than forty years old.The Global Alliance for TB Drug De- velopment（全球结核病药物开发联盟）says its long-term goal is a treatment that could work in as few as ten doses. Which of the following statements is NOT right in Paragraph 2?A: Current treatments of TB take at least six months.B: Shorter treatment program would likely mean more patients cured,and fewer infectious patients.C:The patients have to take a combination of several antibiotic drugs daily.D: The patients should stop taking antibiotic drugs as soon as they feel better.
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How long will the ship stay in the Caribbean?A.Eight days
B.About two weeks
C.One month
D.About three months
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How long will the ship stay in the Caribbean?A.Eight days
B.About two weeks
C.One month
D.About three months
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第一篇New Attempts to Eradicate AIDS VirusA high-profile attempt to eradicate the AIDS virus in a few patients continues to show promise.But researchers won't know for a year or more whether it will work,scientist David Ho told journalists here Wednesday for the Fourth Conference on Viruses and Infections."This is a study that's in progress,"says Ho,head of the Aaron Diamond AIDS Research Center, New York.The study involves 20 people who started combinations of anti-HIV drugs very early in the course of the disease,within 90 days of their infections.They'ye been treated for up to 18 months.Four others have dropped out because of side effects or problems complying with the exacting drug system.The drugs have knocked the AIDS virus down to undetectable levels in the blood of all remaining patients.And,in the latest development,scientists have now tested lymph nodes and semen from a few patients and found no virus reproducing there,Ho says."Bear in mind that undetectable does not equal absent,"Ho says.Ho has calculated that the drugs should be able to wipe out remaining viruses一at least from known reservoirs throughout the body—in two to three years.But the only way to prove eradication would be to stop the drugs and see if the virus comes back.On Wednesday,Ho said he wouldn't ask any patient to consider that step before 2(1/2)years of treatment.And he emphasized that he is not urging widespread adoption of such early,aggressive treatment outside of trials.No one knows the long-term risks.But other scientists are looking at similar experiments.A federally funded study will put 300 patients on triple-drug treatments and then see if some responding well after six months can continue to suppress the virus on just one or two drugs,says researcher Douglas Richman of the University of California,San Diego. Some patients in that study also may be offered the chance to stop therapy after 1 8 months or more,he says. We prove that the drugs have wiped out the remaining viruses by________.A:using up all the drugs at onceB:waiting for the virus to die slowlyC:asking the patients'feeling about the diseaseD:stopping the drugs to see if the virus comes back
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Pregnant Women Warned About ACE InhibitorSome of the most commonly used medicines for high blood pressure are drugs called ACE in-hibitors.Doctors have given these drugs to patients for twenty-five years.A government study in the United States found that the use almost doubled between 1995 and 2000.Doctors have known for years that women should not take ACE inhibitors during the last six months of pregnancy.The medicine can injure the baby.ACE inhibitors,though,have been con-sidered safe when taken during the first three months. But a new study has found that women who take these drugs early in their pregnancy still increase the risk of birth disorders. The study shows that,compared to others,their babies were almost three times as likely to be born with major problems .These included problems with the formation of the brain and nervous system and holes in the heart.The researchers say they found no increased risk in women who took other blood pressure medicines during the first three months.Researchers at Vanderbilt University in Tennessee and Boston University did the study.The New England Journal of Medicine published the results. The researchers studied the records of almost thirty thousand births between 1985 and 2000.Two hun-dred nine babies were born to women who took ACE inhibitors during the first three months of their pregnancies.Eighteen of the babies,or almost nine percent,had major disorders.ACE inhibitors are often given to patients with diabetes. But diabetes during pregnancy can result in birth defects.So the study did not include any women known to be diabetic.ACE inhibi- tors suppress a protein called angiotensin-converting enzyme or ACE.This enzyme produces a chemical in the body that makes blood passages narrow.The drugs increase the flow of blood so pressure is reduced.New drugs are tested on pregnant animals to see if they might cause birth defects in humans. But experts say these tests are not always dependable.The United States Food and Drug Adminis- tration helped pay for the study .The F. D.A.says women who might become pregnant should talk with their doctor about other ways to treat high blood pressure. Evidence showed only a small percentage of babies suffered major disorders______.A: that may cause our blood vessels to become more and more narrowB: for pregnant women to take during their last six months of pregnanciesC: that their likelihood to suffer major problems is two times higher than other babiesD: with their doctors about how to treat their problemsE: because diabetes during pregnancy may sometimes lead to birth defectsF: though their mothers took ACE inhibitors during their first three months of pregnancies
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第二篇Study Says Dogs Can Smell CancerDogs are known for their sense of smell.They can find missing people and things like bombs and illegal drugs.Now a study suggests that the animal known as man's best friend can even find bladder（膀胱）cancer.Cancer cells are thought to produce chemicals with unusual odors（气味）. Researchers think dogs have the ability to smell these odors,even in very small amounts,in urine（尿）.The sense of smell in dogs is thousands of times better than in humans.The study follows reports of cases where,for example,a dog showed great interest in a growth on the leg of its owner.The mole（痣）was later found to be skin cancer.Carolyn Willis led a team of researchers at Arnersham Hospital in England.They trained different kinds of dogs for the experiment.The study involved urine collected from biadder cancer patients,from people with other diseases and from healthy people.Each dog was tested eight times.In each test there were seven samples for the dogs to smell.The dog was supposed to signal the one from a bladder cancer patient by lying down next to it,Two cocker spaniels（短腿长毛垂耳小猎犬）were correct fifty-six percent of the time.But the scientists reported an average success rate of forty-one percent.As a group,the study found that the dogs chose the correct sample twenty-two out of fifty-four times.That is almost three times more often than would be expected by chance alone.The British Medical Journal published the research.In all,thirty-six bladder cancer patients and one hundred and eight other people took part.During training,all the dogs reportedly even identified a cancer in a person who had tested healthy before the study,Doctors found a growth on the person's right kidney(肾）.Bladder cancer is the ninth most common cancer worldwide.The International Agency for Research on Cancer says this disease kills more than one hundred thousand people each year.Doctors say cigarette smoking is the leading cause of bladder cancer. The person who had tested healthy before the studyA:dropped out. B:passed away.C:was found to have cancer. D:was found to remain healthy.
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第一篇New Attempts to Eradicate AIDS VirusA high-profile attempt to eradicate the AIDS virus in a few patients continues to show promise.But researchers won't know for a year or more whether it will work,scientist David Ho told journalists here Wednesday for the Fourth Conference on Viruses and Infections."This is a study that's in progress,"says Ho,head of the Aaron Diamond AIDS Research Center, New York.The study involves 20 people who started combinations of anti-HIV drugs very early in the course of the disease,within 90 days of their infections.They'ye been treated for up to 18 months.Four others have dropped out because of side effects or problems complying with the exacting drug system.The drugs have knocked the AIDS virus down to undetectable levels in the blood of all remaining patients.And,in the latest development,scientists have now tested lymph nodes and semen from a few patients and found no virus reproducing there,Ho says."Bear in mind that undetectable does not equal absent,"Ho says.Ho has calculated that the drugs should be able to wipe out remaining viruses一at least from known reservoirs throughout the body—in two to three years.But the only way to prove eradication would be to stop the drugs and see if the virus comes back.On Wednesday,Ho said he wouldn't ask any patient to consider that step before 2(1/2)years of treatment.And he emphasized that he is not urging widespread adoption of such early,aggressive treatment outside of trials.No one knows the long-term risks.But other scientists are looking at similar experiments.A federally funded study will put 300 patients on triple-drug treatments and then see if some responding well after six months can continue to suppress the virus on just one or two drugs,says researcher Douglas Richman of the University of California,San Diego. Some patients in that study also may be offered the chance to stop therapy after 1 8 months or more,he says. The words"Bear in mind that undetectable does not equal absent" by Ho's means_________.A:AIDS virus can be undetectable in the bloodB:AIDS virus is undetectable in the bloodC:no AIDS virus can be detected in the bloodD:no virus found in the blood means no AIDS
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Pregnant Women Warned About ACE InhibitorSome of the most commonly used medicines for high blood pressure are drugs called ACE in-hibitors.Doctors have given these drugs to patients for twenty-five years.A government study in the United States found that the use almost doubled between 1995 and 2000.Doctors have known for years that women should not take ACE inhibitors during the last six months of pregnancy.The medicine can injure the baby.ACE inhibitors,though,have been con-sidered safe when taken during the first three months. But a new study has found that women who take these drugs early in their pregnancy still increase the risk of birth disorders. The study shows that,compared to others,their babies were almost three times as likely to be born with major problems .These included problems with the formation of the brain and nervous system and holes in the heart.The researchers say they found no increased risk in women who took other blood pressure medicines during the first three months.Researchers at Vanderbilt University in Tennessee and Boston University did the study.The New England Journal of Medicine published the results. The researchers studied the records of almost thirty thousand births between 1985 and 2000.Two hun-dred nine babies were born to women who took ACE inhibitors during the first three months of their pregnancies.Eighteen of the babies,or almost nine percent,had major disorders.ACE inhibitors are often given to patients with diabetes. But diabetes during pregnancy can result in birth defects.So the study did not include any women known to be diabetic.ACE inhibi- tors suppress a protein called angiotensin-converting enzyme or ACE.This enzyme produces a chemical in the body that makes blood passages narrow.The drugs increase the flow of blood so pressure is reduced.New drugs are tested on pregnant animals to see if they might cause birth defects in humans. But experts say these tests are not always dependable.The United States Food and Drug Adminis- tration helped pay for the study .The F. D.A.says women who might become pregnant should talk with their doctor about other ways to treat high blood pressure. Paragraph 5______A: Effects of ACE and ACE InhibitorsB: Wide Use of ACE InhibitorsC: How to Deal with High Blood Pressure in Pregnant WomenD: Damage to Pregnant Women's Future BabiesE: Suggestions on Stopping the Use of ACE InhibitorsF: Relative Safety for Women During the First Three Months of Pregnancies
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第一篇New Attempts to Eradicate AIDS VirusA high-profile attempt to eradicate the AIDS virus in a few patients continues to show promise.But researchers won't know for a year or more whether it will work,scientist David Ho told journalists here Wednesday for the Fourth Conference on Viruses and Infections."This is a study that's in progress,"says Ho,head of the Aaron Diamond AIDS Research Center, New York.The study involves 20 people who started combinations of anti-HIV drugs very early in the course of the disease,within 90 days of their infections.They'ye been treated for up to 18 months.Four others have dropped out because of side effects or problems complying with the exacting drug system.The drugs have knocked the AIDS virus down to undetectable levels in the blood of all remaining patients.And,in the latest development,scientists have now tested lymph nodes and semen from a few patients and found no virus reproducing there,Ho says."Bear in mind that undetectable does not equal absent,"Ho says.Ho has calculated that the drugs should be able to wipe out remaining viruses一at least from known reservoirs throughout the body—in two to three years.But the only way to prove eradication would be to stop the drugs and see if the virus comes back.On Wednesday,Ho said he wouldn't ask any patient to consider that step before 2(1/2)years of treatment.And he emphasized that he is not urging widespread adoption of such early,aggressive treatment outside of trials.No one knows the long-term risks.But other scientists are looking at similar experiments.A federally funded study will put 300 patients on triple-drug treatments and then see if some responding well after six months can continue to suppress the virus on just one or two drugs,says researcher Douglas Richman of the University of California,San Diego. Some patients in that study also may be offered the chance to stop therapy after 1 8 months or more,he says. Other scientists are looking at experiments that are similar in that they are studying_______.A:the ways the patients are treatedB:the size of the experimentC:the cost of the experimentD:the time the experiment takes
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第一篇New Attempts to Eradicate AIDS VirusA high-profile attempt to eradicate the AIDS virus in a few patients continues to show promise.But researchers won't know for a year or more whether it will work,scientist David Ho told journalists here Wednesday for the Fourth Conference on Viruses and Infections."This is a study that's in progress,"says Ho,head of the Aaron Diamond AIDS Research Center, New York.The study involves 20 people who started combinations of anti-HIV drugs very early in the course of the disease,within 90 days of their infections.They'ye been treated for up to 18 months.Four others have dropped out because of side effects or problems complying with the exacting drug system.The drugs have knocked the AIDS virus down to undetectable levels in the blood of all remaining patients.And,in the latest development,scientists have now tested lymph nodes and semen from a few patients and found no virus reproducing there,Ho says."Bear in mind that undetectable does not equal absent,"Ho says.Ho has calculated that the drugs should be able to wipe out remaining viruses一at least from known reservoirs throughout the body—in two to three years.But the only way to prove eradication would be to stop the drugs and see if the virus comes back.On Wednesday,Ho said he wouldn't ask any patient to consider that step before 2(1/2)years of treatment.And he emphasized that he is not urging widespread adoption of such early,aggressive treatment outside of trials.No one knows the long-term risks.But other scientists are looking at similar experiments.A federally funded study will put 300 patients on triple-drug treatments and then see if some responding well after six months can continue to suppress the virus on just one or two drugs,says researcher Douglas Richman of the University of California,San Diego. Some patients in that study also may be offered the chance to stop therapy after 1 8 months or more,he says. Which is NOT true about Ho's study?A:20 patients were involved in the study.B:The patients have used several anti-HIV drugs.C:16 patients withdrew from the experiment.D:The patients have been treated for up to 1 8months.
考题
A.invite constant conflicts with passionate consumers
B.can be used to produce negative effects in marketing
C.may be responsible for fiercer competition
D.deserve all the negative comments about them
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Over（）science parks have been set up by higher education institutions in conjunction with industrial scientists and technologists.A10B20C30D40
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Over（）science parks have been set up by higher education institutions in conjunction with industrial scientists and technologists.A、10B、20C、30D、40
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单选题Each EPIRB required on an OSV shall be tested using the integrated test circuit and output indicator every（）.A
weekB
two weeksC
monthD
two months
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单选题The controversy mentioned in the passage focuses on _____.A
whether psychologists should use drugs to cure their patientsB
how psychologists should treat their patientsC
the fact that all of the drugs have harmful side effectsD
the extent to which drugs should be used to fight psychological illness
考题
单选题An emergency generator, driven by an internal combustion engine, shall be tested under load for a minimum of 2 hours at least once every （）A
weekB
2 weeksC
monthD
3 months
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单选题Scientists say it may be five or six years _____ this medicine is tested on human beings.A
sinceB
beforeC
afterD
when
考题
单选题The vessel’s Emergency Position Indicating Radio beacon (EPIRB) must be tested（）.A
weeklyB
monthlyC
every 2 monthsD
every 3 months
考题
单选题Before they left the factory, all the cars were carefully tested for（）A
defectsB
flawsC
faultsD
errors
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问答题The goals of the scientists, whose training had afforded them extensive experience with cutting-edge methodologies, A Bwere to change the genetic components of the virus and creating a new set of criteria for analyzing the results. C DNo error E
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单选题Cargo vessels being navigated，and fitted with emergency lighting and power systems，shall have their emergency systems tested at least once（）.A
a monthB
in each weekC
in every 6 monthsD
in every 12 months
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单选题On a ship，each emergency generator must be tested at least once each（）.A
weekB
monthC
three monthsD
six months
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