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There may also be other targets not yet explored that affect aging and neuromuscular function. Said Kornfeld: “The process of aging remains mysterious. ”

A. But Komfeld said scientists will not know about the applicability of the drugs in humans until a similar study is done on humans. “What’s very encouraging is that these drugs were developed to treat humans, and they are well understood, because they’ve been used for a long time, ” he said。

B. Later the scientists discovered that two related anticonvulsant drugs also lengthened the lives of the worms-in the case of one drug, by almost 50 percent. “This was a big surprise to use, Komfeld said. ”“We didn’t think anticonvulsant drugs had any particular relationship to aging. That connection was completely unexpected. ”

C. Roundworms are a poor subject for experiments, because they are not like humans, even though their molecules are similar. For example, they have no bones, nor do they show emotions, making it difficult to know how exactly human subjects would react to these drugs in large quantities. However, using the worms allows experiments to be conducted quickly, because they do not live for long。

D. “Somehow the neural activity seems to regulate the aging of all of the body the skin, musculature, and reproductive tract, ” Kornfeld said. “Somehow the nervous system coordinates the progress of all these tissues, evidently, though the life stages. But we don’t know how it does that. ”

E. The discovery may also shed light on the little-understood aging process. Since the drugs act on the neuromuscular systems of both humans and worms, the findings hint at a link between neural activity and aging。

F. Unlike vertebrates, the worms are ideal subjects for the study of aging because of their short life spans, which last only a couple of weeks in a laboratory. The worm is well known in genetics, and the worm’s genome has been sequenced。

G. Use of this drug has been permitted by law since 1998 and wider use is now expected as a result of the studies. “We can clearly link this drug with human aging, but we still need to find proof, says Kornfeld optimistically. ”


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更多 “ There may also be other targets not yet explored that affect aging and neuromuscular function. Said Kornfeld: “The process of aging remains mysterious. ”A. But Komfeld said scientists will not know about the applicability of the drugs in humans until a similar study is done on humans. “What’s very encouraging is that these drugs were developed to treat humans, and they are well understood, because they’ve been used for a long time, ” he said。B. Later the scientists discovered that two related anticonvulsant drugs also lengthened the lives of the worms-in the case of one drug, by almost 50 percent. “This was a big surprise to use, Komfeld said. ”“We didn’t think anticonvulsant drugs had any particular relationship to aging. That connection was completely unexpected. ”C. Roundworms are a poor subject for experiments, because they are not like humans, even though their molecules are similar. For example, they have no bones, nor do they show emotions, making it difficult to know how exactly human subjects would react to these drugs in large quantities. However, using the worms allows experiments to be conducted quickly, because they do not live for long。D. “Somehow the neural activity seems to regulate the aging of all of the body the skin, musculature, and reproductive tract, ” Kornfeld said. “Somehow the nervous system coordinates the progress of all these tissues, evidently, though the life stages. But we don’t know how it does that. ”E. The discovery may also shed light on the little-understood aging process. Since the drugs act on the neuromuscular systems of both humans and worms, the findings hint at a link between neural activity and aging。F. Unlike vertebrates, the worms are ideal subjects for the study of aging because of their short life spans, which last only a couple of weeks in a laboratory. The worm is well known in genetics, and the worm’s genome has been sequenced。G. Use of this drug has been permitted by law since 1998 and wider use is now expected as a result of the studies. “We can clearly link this drug with human aging, but we still need to find proof, says Kornfeld optimistically. ” ” 相关考题
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考题 共用题干 第二篇High Stress May Damage MemoryAccording to a report issued in May 1998,elderly people who have consistently high blood levels of cortisol (皮质醇)don't score as well on memory tests as their peers with lower levels of the stress hormone. What's more,high levels of cortisol are also associated with shrinking of the hippocampus(海马区),a region of the brain that plays a key role in learning and memory.The findings suggest that even cortisol levels in the normal,"healthy"range can actually accelerate brain aging.The study results"now provide substantial evidence that long-term exposure to adrenal(肾上腺的)stress hormones may promote hippocampal aging in normal elderly humans", write Nada Porter and Philip Landfield.Cortisol is a hormone released in response to stress by the adrenal glands(腺),which sit on top of the kidneys(肾).Over a 5-to 6-year period,Dr. Sonia Lupien and his colleagues measured 24-hour cortisol levels in 51 healthy volunteers,most of whom were in their 70s.The researchers tested the volunteers' memory on six people in the increasing/high category and five people in the decreasing/moderate group.The groups did not differ in tests of immediate memory,but the increasing/high cortisol group had other memory problems compared with those in the decreasing/moderate group.The researchers also found that the total volume of the hippocampus in those in the increasing/high group was 14% lower than those in the decreasing/moderate group, although there were no differences in other brain regions.The results suggest that“…brain aging can be accelerated by levels of adrenalhormones that are not generally regarded as pathological(病态的)and that variation within this normal range is related to variation in the rate of brain aging",write Porter and Landfield."This further suggests that chronic stress may accelerate the worsening of the hippocampus." When the levels of cortisol go high,the hippocampusA:may expand. B:may shrink.C:may disappear. D:may function better.

考题 共用题干 第二篇High Stress May Damage MemoryAccording to a report issued in May 1998,elderly people who have consistently high blood levels of cortisol (皮质醇)don't score as well on memory tests as their peers with lower levels of the stress hormone. What's more,high levels of cortisol are also associated with shrinking of the hippocampus(海马区),a region of the brain that plays a key role in learning and memory.The findings suggest that even cortisol levels in the normal,"healthy"range can actually accelerate brain aging.The study results"now provide substantial evidence that long-term exposure to adrenal(肾上腺的)stress hormones may promote hippocampal aging in normal elderly humans", write Nada Porter and Philip Landfield.Cortisol is a hormone released in response to stress by the adrenal glands(腺),which sit on top of the kidneys(肾).Over a 5-to 6-year period,Dr. Sonia Lupien and his colleagues measured 24-hour cortisol levels in 51 healthy volunteers,most of whom were in their 70s.The researchers tested the volunteers' memory on six people in the increasing/high category and five people in the decreasing/moderate group.The groups did not differ in tests of immediate memory,but the increasing/high cortisol group had other memory problems compared with those in the decreasing/moderate group.The researchers also found that the total volume of the hippocampus in those in the increasing/high group was 14% lower than those in the decreasing/moderate group, although there were no differences in other brain regions.The results suggest that“…brain aging can be accelerated by levels of adrenalhormones that are not generally regarded as pathological(病态的)and that variation within this normal range is related to variation in the rate of brain aging",write Porter and Landfield."This further suggests that chronic stress may accelerate the worsening of the hippocampus." According to the passage,when people are under stress,A:the adrenal glands will produce cortisol.B:the kidneys will shrink rapidly.C:the hippocampus will produce cortisol.D:the brain will work more efficiently.

考题 共用题干 第二篇High Stress May Damage MemoryAccording to a report issued in May 1998,elderly people who have consistently high blood levels of cortisol (皮质醇)don't score as well on memory tests as their peers with lower levels of the stress hormone. What's more,high levels of cortisol are also associated with shrinking of the hippocampus(海马区),a region of the brain that plays a key role in learning and memory.The findings suggest that even cortisol levels in the normal,"healthy"range can actually accelerate brain aging.The study results"now provide substantial evidence that long-term exposure to adrenal(肾上腺的)stress hormones may promote hippocampal aging in normal elderly humans", write Nada Porter and Philip Landfield.Cortisol is a hormone released in response to stress by the adrenal glands(腺),which sit on top of the kidneys(肾).Over a 5-to 6-year period,Dr. Sonia Lupien and his colleagues measured 24-hour cortisol levels in 51 healthy volunteers,most of whom were in their 70s.The researchers tested the volunteers' memory on six people in the increasing/high category and five people in the decreasing/moderate group.The groups did not differ in tests of immediate memory,but the increasing/high cortisol group had other memory problems compared with those in the decreasing/moderate group.The researchers also found that the total volume of the hippocampus in those in the increasing/high group was 14% lower than those in the decreasing/moderate group, although there were no differences in other brain regions.The results suggest that“…brain aging can be accelerated by levels of adrenalhormones that are not generally regarded as pathological(病态的)and that variation within this normal range is related to variation in the rate of brain aging",write Porter and Landfield."This further suggests that chronic stress may accelerate the worsening of the hippocampus." Which of the following plays a key role in one's learning and memory?A:The kidneys. B:The adrenal glands.C:The stress hormone. D:The hippocampus.

考题 共用题干 第二篇High Stress May Damage MemoryAccording to a report issued in May 1998,elderly people who have consistently high blood levels of cortisol (皮质醇)don't score as well on memory tests as their peers with lower levels of the stress hormone. What's more,high levels of cortisol are also associated with shrinking of the hippocampus(海马区),a region of the brain that plays a key role in learning and memory.The findings suggest that even cortisol levels in the normal,"healthy"range can actually accelerate brain aging.The study results"now provide substantial evidence that long-term exposure to adrenal(肾上腺的)stress hormones may promote hippocampal aging in normal elderly humans", write Nada Porter and Philip Landfield.Cortisol is a hormone released in response to stress by the adrenal glands(腺),which sit on top of the kidneys(肾).Over a 5-to 6-year period,Dr. Sonia Lupien and his colleagues measured 24-hour cortisol levels in 51 healthy volunteers,most of whom were in their 70s.The researchers tested the volunteers' memory on six people in the increasing/high category and five people in the decreasing/moderate group.The groups did not differ in tests of immediate memory,but the increasing/high cortisol group had other memory problems compared with those in the decreasing/moderate group.The researchers also found that the total volume of the hippocampus in those in the increasing/high group was 14% lower than those in the decreasing/moderate group, although there were no differences in other brain regions.The results suggest that“…brain aging can be accelerated by levels of adrenalhormones that are not generally regarded as pathological(病态的)and that variation within this normal range is related to variation in the rate of brain aging",write Porter and Landfield."This further suggests that chronic stress may accelerate the worsening of the hippocampus." The research conducted by Porter and Landfield shows thatA:the levels of adrenal hormones have nothing to do with brain aging.B:changes in the levels of adrenal hormones can affect brain aging.C:chronic stress may strengthen one's memory.D:the rate of brain aging always remains stable.

考题 共用题干 第二篇High Stress May Damage MemoryAccording to a report issued in May 1998,elderly people who have consistently high blood levels of cortisol (皮质醇)don't score as well on memory tests as their peers with lower levels of the stress hormone. What's more,high levels of cortisol are also associated with shrinking of the hippocampus(海马区),a region of the brain that plays a key role in learning and memory.The findings suggest that even cortisol levels in the normal,"healthy"range can actually accelerate brain aging.The study results"now provide substantial evidence that long-term exposure to adrenal(肾上腺的)stress hormones may promote hippocampal aging in normal elderly humans", write Nada Porter and Philip Landfield.Cortisol is a hormone released in response to stress by the adrenal glands(腺),which sit on top of the kidneys(肾).Over a 5-to 6-year period,Dr. Sonia Lupien and his colleagues measured 24-hour cortisol levels in 51 healthy volunteers,most of whom were in their 70s.The researchers tested the volunteers' memory on six people in the increasing/high category and five people in the decreasing/moderate group.The groups did not differ in tests of immediate memory,but the increasing/high cortisol group had other memory problems compared with those in the decreasing/moderate group.The researchers also found that the total volume of the hippocampus in those in the increasing/high group was 14% lower than those in the decreasing/moderate group, although there were no differences in other brain regions.The results suggest that“…brain aging can be accelerated by levels of adrenalhormones that are not generally regarded as pathological(病态的)and that variation within this normal range is related to variation in the rate of brain aging",write Porter and Landfield."This further suggests that chronic stress may accelerate the worsening of the hippocampus." It appears that when the hippocampus shrinks due to high levels of cortisol,other brain regionsA:may change dramatically. B:may stop functioning.C:may remain unaffected. D:may be seriously damaged,

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